At present, studies on medical cannabis have yielded very encouraging results. Scientists looking at the chemical compounds in cannabis, such as THC and CBD, have discovered that these cannabinoids can work to not only stop the division and growth of tumor cells but also kill the cells directly.
Further, CB-2 agonist decrease hepatic immune cells infiltration, kupffer cell activation, oxidative stress, hepatic injury and fibrogenesis [39–42]. Taken together, our novel observations and previous findings suggest that CB-2 agonist and hemp which has a higher CBD might offer more protection from NAFLD . Regarding nonalcoholic fatty liver disease, a recent study found that those who used cannabis occasionally had a 15% lower risk, and regular users had a 52% lower risk of developing the disease. Although correlative studies should always be taken with a grain of salt, there’s a convincing amount of evidence that the more you use cannabis, the less likely you are to develop liver disease. From alcoholism, sugar addiction, processed food, and obesity, it’s safe to say that liver health should be most people’s top priority.
Does Cbd Get You High?
- saw its lead drug Epidiolex, a CBD-based oral solution, get approved to treat two rare forms of childhood-onset epilepsy.
- But this faith in CBD and its medical benefits may be misplaced, at least according to one new study.
- Another study found it reduced the anguish associated with post-traumatic stress disorder.
- In many respects, CBD is being hailed as an inexpensive cure-all for a number of conditions.
Inside Heart Health:
In addition to other ingredients, cannabis contains tetrahydrocannabinol and cannabidiol . While THC has more effect on the CB-1, CBD act preferentially on CB-2. CB-1 has been shown to be more pro-inflammatory and psychotropic, unlike CB-2, which is more anti-inflammatory and non-psychotropic . Pre-clinical studies have demonstrated that hepatic CB-1 receptors up-regulate hepatic fatty acid production and participate in diet-induced obesity .
Hepatic CB-1 receptors also promote liver fibrosis in both murine and human subjects . In contrast, CB-2 agonists can suppress obesity, steatohepatitis and can additionally protect the liver from ischemic reperfusion injury.
According to a study by a group of researchers at the University of Arkansas, people who consume CBD are at a higher risk for liver toxicity. While there isn’t a lot of research data when it comes to using CBD oil to treat humans with liver disease, many people in the scientific community are very hopeful. There is a decent amount of scientific data to suggest that CBD oil can actually be quite effective in the treatment of liver disease.
Study authors theorized that cannabis may help reduce the inflammation that occurs early among those with ALD, slowing its progression. Many scientists now believe that CBD could damage the liver just like alcohol and other drugs.
30 million Americans have some form of liver disease, and 160 million how to take CBD oil Americans are obese or overweight. However, doctors warn that cannabis use may worsen some liver diseases. For example, patients with hepatitis C virus who use cannabis tend to have more liver scarring than those who don’t. Doctors also say cannabis may not be good for patients with fatty liver disease.
The findings may lead to new cannabis-based treatments for certain liver diseases, say researchers. Study researchers are already working to discover which cannabinoid formulations will provide the most therapeutic benefits. Previous research has shown that cannabinoid receptors in the liver could be potential targets for treating liver disease.